DNA Neutralizing Solution

ItemSizeList PriceQty
351-014-131 1000 mL $63.67
351-014-151 10 L Read more


DNA Neutralizing Solution is used for the isolation of plasmid DNA by alkaline lysis method. Addition of the neutralization solution to lysed bacterial cells adjusts the pH, resulting in precipitation of protein and genomic DNA.

  • Contains 1.5 M NaCl and 1.0 M Tris
  • Filtered through a 0.22 µm membrane
  • DNase tested


DNA Neutralizing solution is used to neutralize fractionated DNA contained in an electrophoresis gel after denaturation and prior to transfer to nitrocellulose or nylon membrane. During DNA isolation after lysis, DNA neutralizing solution is added causing the denatured genomic DNA to precipitate, while the circular, covalently closed plasmid DNA reanneals, remaining in solution.


Max Shelf Life: 36 months

Storage Condition: 15°C to 30°C

Shipping Condition: ambient temperature

Sterile Filtered

DNase Tested

Product and/or packaging contains recycled/renewable content Product and/or packaging is recyclable or reduces waste Product and/or packaging is safer to human and environmental health

UNSPSC: 41116126

Harmonization Code: 3822.00.5090



Additional information

Product Manufacturer

Quality Biological

Product Documentation

Safety Data Sheet 351-014